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Pocomoke River, Maryland
Indian River, Delaware
Neuse and Pamlico Rivers, North Carolina
North Inlet, South Carolina
 
Neuse and Pamlico Rivers, North Carolina

 

The Neuse and Pamlico Estuaries have supported the most extensive outbreaks of Pfiesteria.  The Albemarle-Pamlico Estuarine System is the second largest, after the Chesapeake Bay. 

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